Sunday May 29, 2022
I've Been Thinking:

Tel Aviv University researchers announced that they have identified a previously unknown mechanism shared by mutations in two genes which are thought to cause autism, schizophrenia and certain other conditions.

Researchers also found that an existing experimental drug may be suitable for treating a range of rare syndromes caused by these mutations which impair brain functions.

Their new findings could lead to the development of effective treatments for some cases of autism, schizophrenia and neurodegenerative diseases like Alzheimer’s.

“Some cases of autism are caused by mutations in various genes,” said Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine and the Sagol School of Neuroscience at Tel Aviv University. “Today we know of more than 100 genetic syndromes associated with autism, 10 of which are considered relatively common (though still extremely rare).”

The results of the study were published in the Molecular Psychiatry journal earlier this month.

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