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Israel & Alzheimers
By Micah Halpern

Tuesday September 20, 2022
I've Been Thinking:

A group of Israeli and American researchers have developed a method to detect Alzheimer's disease.  To do so, they examine their patient’s eyes.   

The researchers have proved that the beta-amyloid plaques and abnormal proteins in the retina of the eye can determine Alzheimer’s.

Alzheimer's disease is a progressive neurological disorder.  It causes brain shrinkage and brain cell death. It is the most common cause of dementia.

The research was published in the latest issue of the Israel Medical Association's Hebrew-language journal Harefuah.

Research was conducted by Dr. Keren Wood of the Samson Assuta Ashdod Hospital in Ashdod and Ben-Gurion University of the Negev. along with Idit Maharshak of Wolfson Medical Center in Holon and Sackler Medical School at Tel Aviv University, and with Yosef Koronyo and Maya Koranyo-Hamaoui from Cedars-Sinai Medical Center in Los Angeles, California.

The researchers explain that retinal photoreceptors absorb light and transfer data to the retinal ganglion cell layer. And because the retina is connected to the brain, it appears that changes in this part of the eye reflect disease processes in the brain - including the development of Alzheimer's disease.

During autopsies, beta-amyloid plaques have been found in the retinas of people who died of Alzheimer's disease.

During the study, 10 patients with Alzheimer's disease and six healthy control patients were asked to swallow turmeric, a deep yellow spice that attaches to beta-amyloid plaques. A few days later, their retinas were examined.

The yellow was found to stick to the retinal cells of patients with Alzheimer's disease and not those of healthy patients.

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20 October 2022 10:38 AM in Thoughts


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